Tony D’Urso Show

What happens when you've made an extraordinary discovery, secured patents, and earned recognition for your work — but nobody wants to bring your innovation to market?

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Dr. Nathan Bryan faced that challenge when he stepped beyond academic research and into entrepreneurship. He spent two years pitching investors, struggled to secure funding, and learned firsthand that even a brilliant discovery doesn't guarantee business success. Today, Nathan has built a portfolio of companies worth more than a billion dollars. But his journey reveals something every entrepreneur needs to understand: patents don't guarantee protection, investors don't always share your vision, and your reputation may ultimately be your most valuable asset.

What You'll Learn

• Turning discoveries into businesses: Why a groundbreaking idea isn't enough — and what it takes to bring innovation into the marketplace.

• Protecting intellectual property: How patents can provide a competitive advantage and why they don't guarantee protection from competitors.

• Winning over investors: What Nathan learned from two years of pitching, struggling to raise capital, and finding people who believed in his vision.

• Building trust and credibility: Why your reputation may be your company's most valuable asset — and how to protect it.

• Building lasting customer loyalty: Why delivering on your promises matters more than expensive marketing campaigns and constant customer acquisition.

Sponsors & Resources

Amazon / Movember — Amazon is supporting the Movember Foundation for the fourth year, helping raise awareness for men's health. Explore eligible grooming products from brands including Philips Norelco and DOVE MEN + CARE at Amazon / Movember.

Base44 — Build real apps, websites, and business systems by describing what you need in your own words. Get 30% off the Builder plan for your first year at Base44.

The Southgate Foundation — Quietly making a difference in the lives of people and communities around the world. Learn more at The Southgate Foundation.

About Dr. Nathan Bryan

Dr. Nathan Bryan is a scientist, inventor, and entrepreneur recognized for his pioneering work in nitric oxide research. He earned his PhD from Louisiana State University School of Medicine, completed postdoctoral training at Boston Medical Center, and established his own research laboratory at the University of Texas Health Science Center in Houston. With more than 100 peer-reviewed scientific publications and dozens of patents, Nathan has developed technologies across multiple product categories, including consumer products and pharmaceutical research.

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👉 Explore my bestselling books and the Imen of Atlantis adventure series

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What if the secret to extraordinary business growth isn't more technology, bigger advertising budgets, or another marketing strategy?

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Colin Hodge has helped scale apps to more than 100 million users, discovering along the way that extraordinary growth begins with understanding people. From creating emotional connections and discovering the moments that turn first-time users into loyal customers to avoiding costly AI-driven marketing mistakes, Colin shares practical lessons from building, selling, and buying back businesses.

 What You'll Learn

• Features vs. benefits: How to position your product around what customers actually want and feel.

• The psychology of customer loyalty: Why the IKEA effect can make customers more invested in your product.

• Finding your magic moment: How to identify the experiences that turn new users into long-term customers.

• Sustainable business growth: Why organic growth can be more valuable than continuously increasing paid advertising.

• AI and human empathy: How to use artificial intelligence without losing the judgment and human understanding that customers need.

Sponsors & Resources

 Odoo — Run your business with one integrated platform connecting sales, accounting, inventory, websites, and more. Discover how Odoo can simplify your operations at Odoo.

The Vision Map™ — Get Tony's FREE Vision Map™ Blueprint and begin turning your vision into a clear plan of action.

Hard-Won Answers — Discover Tony's companion podcast featuring focused, actionable answers from extraordinary entrepreneurs. Listen on Apple Podcasts.

The Southgate Foundation — Quietly making a difference for people facing difficult circumstances around the world. Learn more

About Colin Hodge

Colin Hodge is an entrepreneur, growth strategist, and author who has helped grow consumer applications to more than 100 million users. His experience includes building and scaling startups, advising companies on growth, and founding the dating app DOWN, which he sold and subsequently reacquired. Drawing on more than two decades of experience, Colin focuses on the behavioral psychology behind customer acquisition, retention, and sustainable growth.

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¬ Learn more about Colin Hodge

¬ Book: Outrageous Startup Growth: Uncovering the Secrets of User Psychology to Scale Your Success

¬ Get your FREE Vision Map™ Blueprint and let's make your vision happen

What separates people who become business owners from those who remain employees?

Entrepreneur Reed Nyffeler shares how to think like an owner, develop leaders, overcome fear, and create exceptional value.

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Why do talented, capable people stay stuck when they could be building something of their own? Reed Nyffeler has spent nearly two decades developing leaders and helping people make the transition from employee to business owner. He shares why fear keeps people from making the leap, how purpose creates direction, and why one simple change from "Why me?" to "Why not me?" can completely change how you approach opportunity. You'll also discover why Reed stopped giving people answers and started asking questions, how a lesson from his one-year-old daughter changed his leadership, and why developing other leaders is essential if you want your organization to grow beyond you. And as artificial intelligence transforms the workplace, Reed offers another definition of AI: Authentic Interaction. His message is simple: use technology to create more time for human connection – then find what you can do exceptionally well.

What You'll Learn

• Why talented people stay employees instead of becoming owners.

• How to overcome the fear that keeps you from taking action. • Why asking questions can develop stronger, more independent leaders.

• How purpose creates direction for your business and your life.

• Why becoming exceptional may matter even more in the age of AI.

Sponsors

Odoo - Fully integrated business software to help you grow and scale. Learn more at Odoo.

The Southgate Foundation - Quietly making a difference for people facing difficult circumstances around the world. Learn more. 

Advertise on The Tony DUrso Show. For sponsorship opportunities, email: ad-sales@libsyn.com

About Reed Nyffeler

Reed Nyffeler is an entrepreneur, author, and founder and CEO of Signal, a security franchise operating across 48 states and nine countries. Over the course of his career, he has helped hundreds of people move toward business ownership while developing leaders capable of building and growing their own organizations. Reed is the author of Transform Through Purpose and Lead Exponentially. His work focuses on a progression from leading yourself, to developing other leaders, to building organizations that can grow beyond their founders. He also created Next In Leadership to help develop the next generation of leaders through authentic interaction, mentorship, and practical leadership development.

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👉 Learn more about Reed Nyffeler

👉 Book: Lead Exponentially: Your Path to Developing Authentic and Intentional Leaders


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What if you're not nearly as good at reading people as you think? Former Secret Service Special Agent Brad Beeler reveals how to build trust, recognize deception, and get closer to the truth.

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What happens when your first impression is completely wrong – and the truth is staring you in the face? 

After 25 years with the United States Secret Service, Brad Beeler knows that even experienced investigators can misread people.

He shares an extraordinary murder investigation in which his assumptions nearly prevented him from discovering the truth – until another detective asked one simple question.

Discover how to recognize misleading signals, earn trust in the first five minutes, and create conversations where people feel comfortable opening up.

The secret isn't always asking the right question. It's earning the right answer.

Whether you're hiring, negotiating, selling, or leading a team, you'll discover a different way to approach the person sitting across from you.

What You'll Learn

•   Why first impressions can lead you to completely misread someone.

•   How to build trust in the first five minutes of a conversation.

•   What body language and vocal cues can – and cannot – reveal about deception.

•   Why listening and giving someone your full attention create a competitive advantage.

•   How to ask better questions and uncover information others miss.


Sponsors 

Odoo - Fully integrated business software to help you grow and scale. Learn more at Odoo.com/tonydurso.

The Southgate Foundation - Helping widows, orphans and the elderly. Learn more at thesouthgatefoundation.org.

Advertise on The Tony DUrso Show. For sponsorship opportunities, email: ad-sales@libsyn.com

About Brad Beeler

Brad Beeler is a retired United States Secret Service Special Agent with 25 years of experience in criminal investigations, protective operations, and high-stakes communication. He conducted more criminal polygraph examinations than any other agent in Secret Service history and trained investigators and intelligence professionals. Drawing on decades of experience interviewing criminals, victims, and world leaders, Brad now shares practical strategies for building trust, understanding human behavior, and communicating more effectively. He is the author of Tell Me Everything: A Secret Service Agent's Proven Strategies for Earning Trust, Revealing the Truth, and Communicating with Anyone.

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👉 Learn more about Brad Beeler

👉 Book: Tell Me Everything: A Secret Service Agent's Proven Strategies for Earning Trust, Revealing the Truth, and Communicating with Anyone


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Every entrepreneur wants more opportunities. But what if chasing them is actually slowing your growth?

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Sir Richard Harpin started HomeServe with £50,000 and ultimately built it into a company valued at more than £4 billion. But looking back, he believes it might have become twice as large if he had learned earlier what not to pursue.

Richard explains why entrepreneurs become bottlenecks as their companies grow, why execution can beat originality, and why founders should focus on their strengths rather than trying to fix every weakness. He also shares why entrepreneurs need a not-to-do list, how he nearly ran out of money twice, and the leadership changes that helped HomeServe expand around the world. This is a conversation about knowing when to push forward – and when saying no may be the smartest growth strategy of all.

What You'll Learn

•  Why too many opportunities can actually limit growth

•  How founders become bottlenecks as their companies scale

•  Why execution can matter more than having an original idea

•  Why Richard believes every entrepreneur needs a not-to-do list

•  How to evolve from running the business to leading its growth

Sponsors

Shopify
Launch, build, and grow your business with one of the world's leading commerce platforms. Start your free trial at Shopify.com/tony

The Southgate Foundation
Helping widows, orphans and the elderly. Learn more at thesouthgatefoundation.org.

Advertise on The Tony DUrso Show. For sponsorship opportunities, email: ad-sales@libsyn.com

About Sir Richard Harpin

Sir Richard Harpin is the founder of HomeServe, which he helped grow from a £50,000 startup into an international company ultimately acquired in a deal valued at more than £4 billion. After more than three decades building HomeServe, Richard turned his attention to helping other entrepreneurs scale their companies. He is the Growth Partner and owner of Business Leader and author of How to Make a Billion in Nine Steps, which distills the lessons he learned building HomeServe – including the mistakes he believes cost the company years of growth.

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👉 Learn more about Sir Richard Harpin

👉 Book: How to Make a Billion in Nine Steps: INSTANT SUNDAY TIMES BESTSELLER


👉 Get your FREE Vision Map™ Blueprint and let's make your vision happen